FORMA advances great science through merging our ideas with those derived from a broad network of collaborative partnerships built to pursue our long term vision.
We support drug discovery and development through:
At FORMA, our focus first on specific disease mechanisms enables a broad pipeline of multiple lead molecules advancing in parallel, with each additionally informing the progress of other projects.
Mechanisms of disease in which FORMA is identifying targets and developing potential treatments, include:
Proteins are involved in almost every biochemical process in living cells. Protein homeostasis is the body’s balance between building proteins and recycling misfolded or dysfunctional proteins. Diseases associated with an imbalance in protein homeostasis include various cancers, neurodegenerative disorders, and cystic fibrosis
Genes dictate sequencing of amino acids to make proteins and determine how proteins are folded in order to serve specific functions in the body. Epigenetics determines where and how much protein is synthesized. Disrupting disease-associated epigenetic enzymes and proteins offers a new way to treat cancer and other diseases.
In order to build and maintain healthy tissues, the body builds and breaks down proteins—together these processes are called protein metabolism. Protein metabolism is key to immune-mediated control of cellular function.
The immune system is a complex network of cells and processes that protect our bodies from disease. The immune system can cause disease if it targets healthy cells or help the body heal by attacking cancer or infection.
“At FORMA, working as an integrated team is key to unlocking the scientific insights necessary to deliver transformative medicines.”
– John Hohneker, M.D., President, Research & Development
FORMA creates integrated drug discovery teams with broad and deep capabilities in chemistry and biology to find needed medicines. We drive scientific innovation through open data exchange and an innovative Partnership Philosophy that ensures breakthrough ideas are rapidly translated into new drug candidates.
FORMA accelerates research through:
We support drug discovery and development with significant Platform Capabilities .
At FORMA, our collaborative research
culture, in combination with a sense of
urgency on behalf of patients, drives
seamless progress through the drug
discovery and development process,
Our drug discovery and clinical development
research teams work together from start to
finish to create efficiencies that increase speed
across all research stages.
Current Clinical Trials can be found atCLINICALTRIALS.GOV
FORMA creates drug candidate selection criteria that foster early-stage clinical development success.
Together with our strategic partners, we prioritize drug candidates with mechanisms of action in specific patient populations, enabling us to look for early evidence of clinical response and streamline the path to regulatory approval.The safety and efficacy of the drug candidates and their uses under investigation have not been established. There is no guarantee that the agents will receive health authority approval or become commercially available in any country for the uses being investigated.